Product name: Methyldopa
Methyldopa |
|
Systematic (IUPAC) name |
|
(S)-2-amino-3-(3,4-dihydroxyphenyl)-2-methyl-propanoic acid |
|
Identifiers |
|
CAS number |
555-30-6 |
ATC code |
C02AB01 |
PubChem |
CID 4138 |
DrugBank |
APRD01106 |
Chemical data |
|
Formula |
C10H13NO |
Mol. mass |
211.215 g/mol |
Pharmacokinetic data |
|
Bioavailability |
approximately 50% |
Metabolism |
Hepatic |
Half-life |
105 minutes |
Excretion |
Renal for metabolites |
Therapeutic considerations |
|
Pregnancy cat. |
a drug of choice in PIH |
Legal status |
Prescription only |
Routes |
Oral, IV |
Methyldopa (L-α-Methyl-3,4-dihydroxyphenylalanine; Aldomet, Aldoril, Dopamet, Dopegyt, etc.) is a psychoactive drug used as a sympatholytic or antihypertensive. Its use is now deprecated following introduction of alternative safer classes of agents. However, it continues to have a role in otherwise difficult to treat hypertension and gestational hypertension (also known as pregnancy-induced hypertension (PIH)).
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